BMP1 polyclonal antibody
产品名称： BMP1 polyclonal antibody
英文名称： BMP1 polyclonal antibody
产品编号： PAB3670
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BMP1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human BMP1.
- Host:
- Rabbit
- Reactivity:
- Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Bone morphogenetic protein-1 (BMP-1). Identification of the minimal domain structure for procollagen C-proteinase activity.
Hartigan N, Garrigue-Antar L, Kadler KE.J Biol Chem. 2003 May 16;278(20):18045-9. Epub 2003 Mar 13.
- 2.
- Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network.
Leighton M, Kadler KE.J Biol Chem. 2003 May 16;278(20):18478-84. Epub 2003 Mar 11.
- 3.
- Post-translational modification of bone morphogenetic protein-1 is required for secretion and stability of the protein.
Garrigue-Antar L, Hartigan N, Kadler KE.J Biol Chem. 2002 Nov 8;277(45):43327-34. Epub 2002 Sep 5.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of mouse liver tissue lysate (35 ug/lane) with BMP1 polyclonal antibody (Cat # PAB3670).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with BMP1 polyclonal antibody (Cat # PAB3670) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 649
- Protein Accession#:
- P13497
- Gene Name:
- BMP1
- Gene Alias:
- FLJ44432,PCOLC,PCP,TLD,pCP-2
- Gene Description:
- bone morphogenetic protein 1
- Omim ID:
- 112264
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq
- Other Designations:
- procollagen C-endopeptidase,procollagen C-proteinase