PKN1 polyclonal antibody
产品名称： PKN1 polyclonal antibody
英文名称： PKN1 polyclonal antibody
产品编号： PAB0271
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PKN1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 921-929 of human PKN1.
- Sequence:
- EAPTLSPPRDARPLTAAEQ
- Host:
- Rabbit
- Reactivity:
- Dog, Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In serum (0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Frozen sections)
- Immunoprecipitation
- Entrez GeneID:
- 5585
- Gene Name:
- PKN1
- Gene Alias:
- DBK,MGC46204,PAK1,PKN,PKN-ALPHA,PRK1,PRKCL1
- Gene Description:
- protein kinase N1
- Omim ID:
- 601032
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
- Other Designations:
- protein kinase C-like 1,protein kinase C-like PKN,protein kinase C-related kinase 1,serine-threonine kinase N,serine/threonine protein kinase N
- Related Disease