PML FISH Probe
产品名称： PML FISH Probe
英文名称： PML FISH Probe
产品编号： FA0349
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Entrez GeneID:
- 5371
- Gene Name:
- PML
- Gene Alias:
- MYL,PP8675,RNF71,TRIM19
- Gene Description:
- promyelocytic leukemia
- Omim ID:
- 102578
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- promyelocytic leukemia protein,promyelocytic leukemia, inducer of,tripartite motif protein TRIM19