FITC标记的GTP酶IMAP家族成员1抗体
产品名称： FITC标记的GTP酶IMAP家族成员1抗体
英文名称： Anti-GIMAP1/FITC
产品编号： HZ-8267R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-GIMAP1/FITC Conjugated antibody
FITC标记的GTP酶IMAP家族成员1抗体
| 产品编号 | bs-8267R-FITC |
| 英文名称 | Anti-GIMAP1/FITC |
| 中文名称 | FITC标记的GTP酶IMAP家族成员1抗体 |
| 别 名 | GIMA1_HUMAN; GIMAP1; GTPase IMAP family member 1; hIMAP1; Immunity-associated protein 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GIMAP1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP1 (GTPase, IMAP family member 1), also known as IMAP1 (immunity-associated protein 1), HIMAP1 or IMAP38, is a 306 amino acid single-pass type IV membrane protein of the endoplasmic reticulum (ER) belonging to the GIMAP family. Encoded by a gene located on human chromosome 7, GIMAP1 is expressed primarily in spleen with lower levels found in lymph node. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity). Subcellular Location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane (By similarity). Tissue Specificity: Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. Similarity: Belongs to the IAN GTP-binding protein family. Database links: UniProtKB/Swiss-Prot: Q8WWP7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
免疫相关蛋白（GIMAP）家族的GTPase包括七个成员，它们由居住在人类7号染色体上的基因表达。GIMAP蛋白参与了淋巴髓鞘细胞存活的调节。GIMAP1（GTPASE，IMAP家族成员1），也称为IMAP1（免疫相关蛋白1），HIMAP1或IMAP38，是属于GIMAP家族的内质网（ER）的306氨基酸单程型IV膜蛋白。GIMAP1主要编码于位于人类7号染色体上的基因，主要表达于脾中，淋巴结中发现的水平较低。第7号染色体包含1000多个基因，包括人类基因组的5%，并与成骨不全、PAND综合征、Lissencephaly、瓜氨酸血症和SuWakman钻石综合征有关。