RGS3 polyclonal antibody
产品名称： RGS3 polyclonal antibody
英文名称： RGS3 polyclonal antibody
产品编号： PAB14588
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RGS3.
- Immunogen:
- A synthetic peptide corresponding to amino acids 111-129 of human RGS3.
- Sequence:
- DSYTREHTKDNLQSVTRGC
- Host:
- Rabbit
- Reactivity:
- Bovine, Chicken, Chimpanzee, Human, Mouse, Rat
- Specificity:
- The amino acid sequence used as immunogen is 100% homologous in human, chimpanzee and cow, 89% homologous in mouse and rat, and 84% homologous in chicken.
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.025% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons.
Tosetti P, Pathak N, Jacob MH, Dunlap K.Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7337-42. Epub 2003 May 27.
- 2.
- Regulation of RGS3 and RGS10 palmitoylation by GnRH.
Castro-Fernandez C, Janovick JA, Brothers SP, Fisher RA, Ji TH, Conn PM.Endocrinology. 2002 Apr;143(4):1310-7.
- 3.
- Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction.
Lu Q, Sun EE, Klein RS, Flanagan JG.Cell. 2001 Apr 6;105(1):69-79.
- Application Image
- ELISA
- Entrez GeneID:
- 5998
- Protein Accession#:
- NP_652759
- Gene Name:
- RGS3
- Gene Alias:
- C2PA,FLJ20370,FLJ31516,FLJ90496,PDZ-RGS3,RGP3
- Gene Description:
- regulator of G-protein signaling 3
- Omim ID:
- 602189
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022813,OTTHUMP00000022814,OTTHUMP00000022815,regulator of G-protein signalling 3
- Gene Pathway