NPTX2 polyclonal antibody
产品名称： NPTX2 polyclonal antibody
英文名称： NPTX2 polyclonal antibody
产品编号： PAB2556
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NPTX2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NPTX2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Quantitative analysis of NPTX2 hypermethylation is a promising molecular diagnostic marker for pancreatic cancer.
Park JK, Ryu JK, Lee KH, Lee JK, Yoon WJ, Lee SH, Yoo JW, Woo SM, Lee GY, Lee CH, Kim YT, Yoon YB.Pancreas. 2007 Oct;35(3):e9-15.
- 2.
- No association between the neuronal pentraxin II gene polymorphism and autism.
Marui T, Koishi S, Funatogawa I, Yamamoto K, Matsumoto H, Hashimoto O, Ishijima M, Nanba E, Nishida H, Sugiyama T, Kasai K, Watanabe K, Kano Y, Kato N, Sasaki T.Prog Neuropsychopharmacol Biol Psychiatry. 2007 May 9;31(4):940-3. Epub 2007 Mar 3.
- 3.
- Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2.
Kirkpatrick LL, Matzuk MM, Dodds DC, Perin MS.J Biol Chem. 2000 Jun 9;275(23):17786-92.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of NPTX2 (arrow) using rabbit NPTX2 polyclonal antibody (Cat # PAB2556). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NPTX2 gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human testis tissue reacted with NPTX2 polyclonal antibody (Cat # PAB2556) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Entrez GeneID:
- 4885
- Protein Accession#:
- NP_002514;P47972
- Gene Name:
- NPTX2
- Gene Alias:
- NARP,NP-II,NP2
- Gene Description:
- neuronal pentraxin II
- Omim ID:
- 600750
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq
- Other Designations:
- apexin,neuronal activity-regulated pentaxin,pentraxin II