IL16 monoclonal antibody, clone J2F10
产品名称: IL16 monoclonal antibody, clone J2F10
英文名称: IL16 monoclonal antibody, clone J2F10
产品编号: MAB2038
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant IL16.
- Immunogen:
- Recombinant protein corresponding to amino acids 502-631 of human IL16.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Preferential migration of T regulatory cells induced by IL-16.
McFadden C, Morgan R, Rahangdale S, Green D, Yamasaki H, Center D, Cruikshank W.J Immunol. 2007 Nov 15;179(10):6439-45.
- 2.
- CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration.
Bernstein HB, Plasterer MC, Schiff SE, Kitchen CM, Kitchen S, Zack JA.J Immunol. 2006 Sep 15;177(6):3669-76.
- 3.
- Interleukin-16.
Cruikshank WW, Kornfeld H, Center DM.J Leukoc Biol. 2000 Jun;67(6):757-66.
- Entrez GeneID:
- 3603
- Protein Accession#:
- NP_004504
- Gene Name:
- IL16
- Gene Alias:
- FLJ16806,FLJ42735,FLJ44234,HsT19289,IL-16,LCF,prIL-16
- Gene Description:
- interleukin 16 (lymphocyte chemoattractant factor)
- Omim ID:
- 603035
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000190849,OTTHUMP00000190850,interleukin 16,lymphocyte chemoattractant factor
- Related Disease
- Asthma
- Asthma
- Biliary Tract Neoplasms
- Bronchiolitis, Viral
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Papillary
- Carcinoma, Renal Cell
- Cardiovascular Diseases
- Celiac Disease
- Chronic Disease
- Colorectal Neoplasms
- Dermatitis, Allergic Contact
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- DNA Damage
- Edema
- Endometriosis
- Esophagitis
- Genetic Predisposition to Disease